Atypical
antipsychotics
[back] Toxic Psychiatry
[Wikipedia] The atypical antipsychotics (also known as second generation antipsychotics) are a class of prescription medications used to treat psychiatric conditions. All atypical antipsychotics are FDA approved for use in the treatment of schizophrenia. Some carry FDA approved indications for acute mania, bipolar mania, psychotic agitation, bipolar maintenance, and other indications.
Clozapine (sold as Clozaril,
Leponex, Fazaclo, Froidir; Gen-Clozapine in Canada;
Clozaril, Denzapine, Zaponex in the UK; Klozapol in
Poland)
Risperidone (Risperdal) (FDA-approval: 1993) Available in oral tablets,
dissolving tablets, liquid form, and extended release intramusclar injection.
Olanzapine (Zyprexa) (FDA-approval: 1996)
Available in oral tablets, dissolving tablets, and intramuscular injection.
Quetiapine (Seroquel) (FDA-approval: 1997) Available only in oral tablets.
Ziprasidone (Geodon) (FDA-approval: 2001) Available in oral capsules and
intramuscular injection.
Aripiprazole (Abilify) (FDA)-approval: 2002) Available in oral tablets and
dissolving tablets.
Sertindole (Serlect, Serdolect) (Not approved by the FDA for use in the USA).
Zotepine (Not approved by the FDA for use in the USA).
Amisulpride (Not approved by the FDA for use in the USA).
Risperidone
Quetiapine (Seroquel, Xeroquel, Ketipinor)
Is The Schizophrenia Mortality Study In The Lancet CREDIBLE?
A study purporting to analyze mortality rates of 66, 881 schizophrenia patients
in Finland (1973 to 2005) was published in the prestigious journal, The Lancet.
A critical analysis by psychiatrist, Grace Jackson, MD, identifies fatal flaws
in the study design and numerous methodological artefacts that introduced bias
which minimized the detection of drug-related mortality. The authors’
conclusions favoring the long-term use of second-generation antipsychotics, and
Clozaril in particular, as Dr. Jackson demonstrates, are not supported by their
study design: indeed, their "favorable" conclusions about patients' mortality
were based upon numerous confounders (methodological tricks and problems) which
mitigated the detection of actual drug-associated mortality.
Vera Hassner Sharav, AHRP/The Lancet
Articles
[2009 May Risperdal ] ADHD
treatment causes young boys to develop female breasts
[2009 March] Hundreds of deaths linked to schizophrenia drug clozapine Fifty people die each year and hundreds more suffer serious side-effects as the result of taking powerful tranquillisers prescribed by the NHS....Data from the medicine watchdog’s own reporting scheme suggests that clozapine, a drug taken by schizophrenia patients, has been linked to 950 deaths since being licensed in 1990 — equivalent to nearly one fatality a week.
Zyprexa: A Prescription for Diabetes, Disease and Early Death by Leonard Roy Frank
[2005 June] Eli Lilly Settles Zyprexa/Diabetes Cases for $690 Million
[Nov 2004] Eli Lilly’s highly touted new anti-psychotic, Zyprexa
[2009 March] Powerful proponent of psychiatric drugs for children primed for a fall
[2008 Nov] Research Center Tied to Drug Company
Antipsychotics Now Top Revenue Producers In US, Topping Cholesterol
Drugs
IMS Health reports that in 2008, sales in the US of antipsychotics (used
for absolutely every alleged mental disorder under the sun) in 2008
reached $14.6 billion, topping lipid regulators (ie, statins, etc.)
which hit $14.5 billion in US sales.