Carolyn Gallagher a; Melody Goodman a. Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years

Affiliation:   a Graduate Program in Public Health, Stony Brook
University Medical Center, Health Sciences Center, New York, USA

This study investigated the association between vaccination with the
Hepatitis B triple series vaccine prior to 2000 and developmental
disability in children aged 1-9 years (n = 1824), proxied by parental
report that their child receives early intervention or special
education services (EIS). National Health and Nutrition Examination
Survey 1999-2000 data were analyzed and adjusted for survey design by
Taylor Linearization using SAS version 9.1 software, with SAS callable
SUDAAN version 9.0.1. The odds of receiving EIS were approximately
nine times as great for vaccinated boys (n = 46) as for unvaccinated
boys (n = 7), after adjustment for confounders. This study found
statistically significant evidence to suggest that boys in United
States who were vaccinated with the triple series Hepatitis B vaccine,
during the time period in which vaccines were manufactured with
thimerosal, were more susceptible to developmental disability than
were unvaccinated boys.
Keywords: early intervention; special education services;
developmental disability; Hepatitis B vaccine triple series