Meningococcal vaccine citations
Meningitis vaccination Meningitis
A, et al. Adverse events temporally associated with meningococcal
vaccines. CMAJ. 1996 Feb 15;154(4):503-7. PMID: 8630839; UI: 96229943.
MO, et al. Acute disseminated encephalomyelitis and meningococcal A and C
vaccine: case report]. Arq Neuropsiquiatr. 1997 Sep;55(3B):632-5. Portugese. PMID:
9629418; UI: 98293063 Servico de Neurologia, Hospital Universitario Clementino Fraga
Filho, Rio de Janeiro RJ, Brasil.
A 25-year-old women developed acute disseminated post-vaccinal encephalomyelitis (ADEM)
following vaccination with A plus C meningococcal vaccine (Pasteur-Merieux). Fast
disappearance of symptoms and gradual resolution of MRI demyelinating lesions occurred
after steroid treatment with high doses of intravenous methylprednisolone. To our
knowledge, ADEM has not been previously described in association with meningococcal
vaccine. Although most cases of ADEM occur following viral infections and vaccination, the
syndrome has previously been related to leptospirosis and Mycoplasma pneumoniae
infections. This suggests that it may also be related to exposure to
polysaccharide-protein vaccines such as the Group A plus Group C meningococcal vaccine.
PMID: 9629418, UI: 98293063
authors listed] [Adverse effects associated with meningococcal A and C vaccine. Data
from The Spanish Drug Surveillance System]. Gac Sanit. 1999 Nov 1;13(6):462-467. Spanish.
[Record as supplied by publisher]PMID: 10620316.