DPT/DT/DTPH/aP  Allergies

 and how do we know that a 2 month old getting his/her first DTaP has a milk allergy, if breastfed and never had milk?

Sheri

Sent by Dawn Richardson, director of www.NVICAdvacacy.org and PROVE www.vaccineinfo.net
 
http://ainotes.wikispaces.com/file/view/Allergic+Reactions+to+DTaP+-+AAAAI+2011.pdf
2011
Allergic Reactions to Diphtheria, Tetanus, and Acellular Pertussis Vaccines Among Children with Milk Allergy

J. D. Kattan, A. L. Cox, A. Nowak-Wegrzyn, G. Gimenez, L. Bardina,
H. A. Sampson, S. H. Sicherer;
Mt. Sinai School of Medicine, New York, NY.

RATIONALE: Vaccines containing diphtheria, tetanus, and acellular pertussis
are processed in medium containing casamino acids derived from
cow’s milk; several milk allergic children have reported allergic reactions
following administration of these vaccines.

METHODS: This was a chart review of patients seen in our practice who
had reported allergic reactions after receiving tetanus vaccines (primary or
booster doses) from September 2007 to March 2010. An inhibition-ELISA
was performed to determine the presence of milk protein in the vaccines.

RESULTS:We identified seven patients (5 male, 2 female; median age 11
years; range: 5-17), who reported convincing allergic reactions to tetanus
vaccines. Six patients had prior allergic reactions to cow’s milk, including
severe reactions (5) and or reactions to trace exposures (4); one was diagnosed
with milk allergy based on serologic testing. All patients had elevated
milk specific IgE levels documented within 2 years of their
reactions to the vaccine: 59, 96, and 5 patients >100 kUA/L. Each reported
symptoms consistent with a diagnosis of anaphylaxis promptly after receiving
the vaccine. Symptoms included: wheezing (5/7), urticaria (5/7),
sneezing/nasal congestion (3/7), angioedema (3/7), and repetitive cough
(2/7). Treatments included antihistamines (5/7), epinephrine (3/7), inhaled
beta-agonists (3/7), and corticosteroids (2/7). Assays were performed on 2
different lots of the tetanus, diphtheria, and acellular pertussis vaccine,
confirming the presence of milk protein in one lot (30 ng/mL).

CONCLUSIONS: Vaccines containing tetanus, diphtheria, and acellular
pertussis derived from broths containing casamino acids may present a
risk to persons with severe milk allergy.